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by Nisole, S. et al.INSERM UMR-S 747 Paris, France ; Université Paris Descartes Paris, France Finally, the key players involved in the degradation of the PML isoforms in response to As2O3 or other...

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by Ohgiya, D. et al.Division of Hematology/Oncology, Department of Internal Medicine, Tokai University School of Medicine, Kanagawa, JapanAssociation of promyelocytic leukemia protein with expression...

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by Katome, T. et al.Department of Ophthalmology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, JapanExpression of promyelocytic leukemia protein and vascular...

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by Carracedo, A. et al.Cancer Genetics Program, Beth Israel Deaconess Cancer Center, Department of Medicine, Harvard Medical School, USA Indeed, PML expression in breast cancer correlated strikingly...

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by Demmer, P.Text changed: ... ... its acetylation levels [Ref].Targeting of the oligomerization of PML-RARalpha through coilded coiled-coil-domain (PCC) peptides leads to an inhibition of the...

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by Demmer, P.Text changed: ... ... that PML regulates p73 stability by positively modulating its acetylation levels [Ref].Targeting of the oligomerization of PML-RARalpha through coilded-coil-domain...

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by Lång, E. et al.Department of Microbiology, Institute of Clinical Biochemistry and Centre of Molecular Biology and Neuroscience, Oslo University Hospital and University of Oslo, Rikshospitalet,...

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by Wolyniec, K. et al.Research Division, The Peter MacCallum Cancer Centre, East Melbourne, Australia; Our findings demonstrate that E6AP-mediated down-regulation of PML-induced senescence is...

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by Reichelt, M. et al.Departments of Pediatrics and Microbiology & Immunology, Stanford University School of Medicine, Stanford, California, United States of America3D Reconstruction of VZV...

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by Satow, R. et al.Division of Chemotherapy and Clinical Research, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan; Laboratory of Genome and Biosignal, JapanΒ-catenin interacts with PML...

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by Amare, P.K. et al.Cancer Cytogenetics Laboratory, Tata Memorial Hospital, Mumbai, IndiaCharacterization of cryptic rearrangements, deletion, complex variants of PML, RARA in acute promyelocytic...

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by Liu, J. et al.Department of Biochemistry and Molecular Biology, Beijing Institute of Radiation Medicine, Beijing, 100850, ChinaPromyelocytic Leukemia Protein Interacts with Werner Syndrome Helicase...

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by Yen, C.C. et al.Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, TaiwanOnly tumor differentiation (P = 0.016), distant metastasis (P = 0.001),...

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by Kepkay, R. et al.Department of Pathology, Dalhousie University, Halifax, CanadaAlthough PML NB number could be restored by complementation with wild-type KAP1, both the loss of KAP1 or...

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by Kim, H.J. et al.Department of Physiology, School of Medicine, Ewha Womans University, Seoul, South Korea Based on these results, we propose that loss of PML protein expression in gastric cancer...

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by Reineke, E.L. et al.Department of Biochemistry, School of Medicine, Case Western Reserve University, Case Comprehensive Cancer Center, USAWe show that H(2)O(2) up-regulates and IGF-1 down-regulates...

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by Yan, J. et al.Shanghai Institute of Hematology, Shanghai Jiaotong University School of Medicine, Shanghai 200025, ChinaPML/RARalpha fusion protein transactivates the tissue factor promoter through...

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by Wang, K. et al.Sino-French Research Center for Life Sciences and Genomics, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, ChinaPML/RARalpha targets promoter regions containing...

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by Xue, Y. et al.Department of Urology, Xi'an Jiaotong University, Xi'an 710061, Shaanxi, ChinaOur data indicate that suppression of telomerase could activate the PML-dependent p53 signaling pathway...

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by Granito, A. et al.Dipartimento di Medicina Clinica, Alma Mater Studiorum University of Bologna, ItalyPML nuclear body component Sp140 is a novel autoantigen in primary biliary cirrhosis.Am. J....

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by Vincenzi, B. et al.Department of Oncology, University Campus Bio-Medico, ItalyIn particular PML protein resulted significantly down-regulated in myxoid liposarcoma and in dedifferentiated...

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by García, C.C. et al.Laboratory of Virology, Department of Biological Chemistry, School of Sciences, University of Buenos Aires, ArgentinaIn HepG2 cells infected with LCMV or transiently transfected...

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by Percherancier, Y. et al.Text changed: Using this sensitive and quantitative SUMO BRET assay that distinguishes PML sumoylation from SBD-mediated PML/SUMO non-covalent interactions, we probed the...

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by Li, W. et al.Department of Viral Immunology, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, ChinaWe investigated the role of PML...

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by Moran, D.M. et al.Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USAPuromycin-based vectors promote a ROS-dependent recruitment of PML to nuclear...

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by Zannini, L. et al.Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale Tumori, Milano 20133, ItalyREGgamma/PA28gamma proteasome activator interacts with PML and Chk2 and affects...

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by Sobol, P.T. et al.Departments of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, CanadaDisruption of PML signaling through overexpression of the dominant-negative...

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by Lee, J.S. et al.Department of Anatomy and Cell Biology, Dong-A University College of Medicine and Medical Science Research Center, 3-1 Dongdaesin-dong, Seo-gu, South KoreaWe observed that...

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by Park, T.S. et al.Department of Laboratory Medicine, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-gu, KoreaAcute promyelocytic leukemia with insertion of PML exon 7a and partial...

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by Brown, N.J. et al.Department of Medical and Molecular Genetics, King's College London School of Medicine, London, UKOver a decade ago, PML-NBs were found to be disrupted in acute promyelocytic...

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by Chung, Y.L. et al.Department of Radiation Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, TaiwanThe enhanced protein-protein interaction between PML and HBV-core inhibited PML-mediated...

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by Plevova, P. et al.Department of Medical Genetics, Faculty Hospital of Ostrava, Czech RepublicGermline disruption of the PML gene is probably not associated with a highly penetrant susceptibility to...

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by Kuwayama, K. et al.Department of Neurosurgery, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, JapanPromyelocytic leukemia protein induces apoptosis due to...

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by Xu, G.L. et al.State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, ChinaTTRAP colocalized with three important PML NBs-associated...

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by Reineke, E.L. et al.Department of Biochemistry, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, USAFunctionally, we show that in the MDA-MB-231 breast cancer cell line...

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by Sieben, M. et al.First Department of Internal Medicine of Johannes Gutenberg University of Mainz, Mainz, GermanyKilling of p53-deficient hepatoma cells by parvovirus H-1 and chemotherapeutics...

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by Sivachandran, N. et al.Department of Molecular Genetics, University of Toronto, Toronto, Ontario, CanadaEpstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of...

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by Ullman, A.J. et al.Department of Molecular Genetics and Microbiology, School of Medicine, Stony Brook University, Stony Brook, USACellular proteins PML and Daxx mediate an innate antiviral defense...

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by Gao, C. et al.Department of Biochemistry, School of Medicine, Case Western Reserve University, 10900 Euclid Ave., USAHDAC7 coexpression stimulates PML sumoylation independent of its HDAC...

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by Matsuo, T. et al.Department of Artificial Joints and Biomaterials, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JapanAll liposarcoma patients without expression of PML...

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by Shima, Y. et al.Molecular Oncology Division, National Cancer Center Research Institute, Tokyo, JapanOur findings suggest that PML stabilizes the transcription factor complex by protecting HIPK2 and...

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by Lo, Y.H. et al.Graduate Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, ROCThe unexpected coupling of PML with NFAT reveals a novel mechanism underlying the diverse...

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by Hayakawa, F. et al.Text changed: PML is involved in trichostatin A-induced apoptosis and PML with an acetylation-defective mutation shows an inability to mediate apoptosis, suggesting the...

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by Li, L. et al.Department of Cell Biology, Key Laboratory of The Education Ministry for Cell Differentiation and Apoptosis, Institutes of Medical Sciencies, Shanghai Jiao Tong University School of...

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by Tavalai, N. et al.Institut für Klinische und Molekulare Virologie, University Hospital Erlangen, Schlossgarten 4, 91054 Erlangen, GermanyNuclear domain 10 components promyelocytic leukemia protein...

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by Son, S.H. et al.Asan Institute for Life Sciences, University of Ulsan College of Medicine, Seoul, Republic of KoreaRetinoic acid attenuates promyelocytic leukemia protein-induced cell death in...

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by Chen, Y. et al.Promyelocytic Leukemia Protein Isoform II Promotes Transcription Factor Recruitment To Activate Interferon Beta and Interferon-Responsive Gene Expression.Mol. Cell. Biol. 2015;...

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by Guan, D. et al.The function, regulation and therapeutic implications of the tumor suppressor protein, PML.Cell. Biosci. 2015; 60[See paper]

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by Ichikawa, H. et al.Prognostic significance of promyelocytic leukemia expression in gastrointestinal stromal tumor; integrated proteomic and transcriptomic analysis.Cancer Sci. 2015; 1:115-24[See...

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by Xu, Z. et al. However, overexpression of PML in gastric cancer cells significantly increased cell apoptosis, resulting in decreases in cell growth, which seemed to require the presence of...

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